Primary endpoint publication 

June 20, 2019
N Engl J Med 2019; 380:2418-2428; 
​DOI: 10.1056/NEJMoa1716734

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Study Design

MR-INFORM is an investigator initiated, international, multi-centre, randomized, controlled outcome trial, comparing state of the art (invasive angiography with fractional flow reserve) with CMR perfusion imaging in patients with high pretest likelihood for coronary artery disease.
Study registration: NCT01236807
Methods publication:
http://www.jcmr-online.com/content/14/1/65
Primary endpoint publication:
​https://www.nejm.org/doi/full/10.1056/NEJMoa1716734?query=TOC

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Current Status

1.9.2015: Recruitment completed
5.9.2016: 1 year follow-up completed
3.2.2017: database closed
17.3.2017: Late breaking clinical trial presentation @ ACC (slides available here; video interview available here)
20.06.2019: Published @NEJM, full paper available here

Participating Sites

Global Chief Investigator: Prof. Eike Nagel
Principal Investigators
Guy's and St. Thomas' Hospital - Prof. Eike Nagel
King's College Hospital - Prof. Ajay Shah
Barts Heart Centre - Dr. Alexander Sirka
Leeds General Infirmary - Prof. John Greenwood
Glenfield Hospital Leicester - Dr. Gerry McCann
Golden Jubilee Hospital Glasgow - Prof. Colin Berry
Bristol Heart Institute - Dr. Chiara Bucciarelli-Ducci
Freeman Hospital Newcastle - Dr. Rajiv Das
Royal Brompton & Harefield Hospitals - Dr. Joyce Wong
Gaia Hospital Porto - Dr. Nuno Bettencourt
Helios Klinikum Berlin-Buch - Prof. Jeanette Schulz-Menger
Elisabeth Krankenhaus Essen - Dr. Oliver Bruder
Herzzentrum Leipzig - Dr. G. Fürnau
Uniklinik Heidelberg - Dr. Sebastian Buss
Robert-Bosch Krankenhaus Stuttgart - Prof. Heiko Mahrholdt
Flinders Medical Centre Adelaide - Prof Jospeh Selvanayagam

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